Chapter 1: AI in Personalized Nutrition

Authors

Synopsis

Author

Dr. Venkateswara Reddy Basu,

Professor and Head, Department of Pharmaceutics, Sri.K.V.College of Pharmacy, Chikkaballapura, Karnataka, India

Abstract

The transition from broad, population-based dietary guidelines to precision nutrition represents a fundamental evolution in healthcare, necessitated by the failure of "one-size-fits-all" approaches to address the rising burden of chronic metabolic diseases. Personalized nutrition operates on the premise that biological responses to dietary intake are highly variable, dictated by a unique interplay of genetic architecture, gut microbiome composition, and lifestyle factors. Artificial Intelligence serves as the indispensable engine for this paradigm, providing the computational capacity to aggregate and analyze vast, heterogeneous datasets ranging from single nucleotide polymorphisms and transcriptomic profiles to real-time blood biomarkers and continuous glucose monitoring data. Machine learning algorithms construct robust predictive models that forecast individual glycemic and lipemic responses by leveraging these high-dimensional inputs, enabling the generation of tailored dietary recommendations optimized for specific metabolic goals. Beyond the scope of individual planning, AI tools are reshaping the landscape of nutritional epidemiology by establishing rigorous causal links between food components and disease phenotypes. Natural Language Processing algorithms mine the sprawling corpus of scientific literature to extract latent associations between bioactive compounds and health outcomes, disentangling the complex web of nutrient interactions. Simultaneously, advanced machine learning models identify non-linear correlations within large-scale cohort data, revealing how specific dietary patterns influence disease risk.

Keywords: Precision Nutrition, Nutrigenomics, Gut Microbiome, Glycemic Prediction, Digital Twin, Natural Language Processing (NLP)

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Published

25 December 2025

How to Cite

Chapter 1: AI in Personalized Nutrition. (2025). In ML in Pharmacognosy & Biotech Discovery (pp. 001-021). ThinkPlus Pharma Publications. https://doi.org/10.69613/p3hzym19